James W. Guo, MD

Academic work

Research

Understanding how cardiovascular health develops over time—and how that knowledge can inform prevention.

Research interests

Health across the life course

Cardiovascular health in young adulthood, its changes over time, and its relationship to later cardiovascular disease and organ damage.

Risk & prevention

Long-term cardiovascular risk prediction, chronic disease, and the role of healthcare access in differences in cardiovascular health.

Imaging & emerging methods

Cardiac imaging and artificial intelligence, alongside work on epigenomic and transcriptomic markers of cardiovascular disease.

Selected publications

Google Scholar

Ongoing work

Manuscript in submission · September 2026

Long-term prediction of atherosclerotic cardiovascular disease

Development and validation of risk models using the Cardiovascular Lifetime Risk Pooling Project.

Manuscript in revision · September 2026

Healthcare access and disparities in cardiovascular health

Examining the impact of healthcare access on racial disparities in cardiovascular health in the CARDIA study.

Selected conference abstracts